Continuous Renal Replacement Therapy Market 2022| Worldwide Share, Global Trends, Boost Growth, Fuel Demand by 2030
Manufacturers Provide Improved Health Systems to Support Extracorporeal Therapies
Growing incidences of acute kidney injury (AKI) have catalyzed the need for improved and quality treatment therapies in the continuous renal replacement therapy (CRRT) landscape. South East Asia and South America, individually, account for ~31% each, of the hospitalized population suffering from acute kidney injury in 2018. With the help of several clinical trials, continuous venovenous haemodiafiltration (CVVHDF) and the continuous venovenous heamofiltration (CVVHF) mode of therapies have helped improve the survival rates in patients suffering from sepsis-induced acute kidney injury (SAKI).
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As such, healthcare providers in hospitals are adopting continuous extracorporeal therapies to cater to the growing need for multi-organ support in critically-ill patients. The introduction of continuous renal replacement therapy has helped healthcare providers safely perform extracorporeal therapies in intensive care units (ICUs) that are less equipped with dialysis infrastructure. New advancements in continuous renal replacement therapy have also helped provide improved medical care to patients with hemodynamic tolerance concerns. Thus, manufacturers should innovate on venovenous systems and modern integrated full-volume pump monitors to help healthcare institutions carry out safe extracorporeal therapies.
Dynamic CRRT Aids Healthcare Providers in Treating Hemodynamically-unstable Patients
Manufacturers are focusing on developing treatment options for acute hemodynamically-unstable patients. Due to rising intolerance towards dialysis therapy, manufacturers are creating more awareness for continuous renal replacement therapy, as this therapy enables slow and constant fluid removal. The success rate of continuous renal replacement therapy has helped healthcare providers improve patient survival rates and renal function recovery.
The continuous renal replacement therapy landscape is undergoing a shift from renal ‘replacement’ to renal ‘support’ therapies. The term ‘dynamic’ CRRT is being adopted by healthcare providers to fast-track treatment processes that are adaptable to the frequently changing health status of critically-ill patients.
Since, healthcare professionals in clinics have limited investment capacities, technological improvements in hardware and software for continuous renal replacement are providing guidance to them on numerous aspects regarding CRRT. Also, the introduction of renal tubule assistive devices (RADs) serves as an efficacious option to bioartificial kidney devices for patients suffering from acute kidney injury.
Smart Decision Software Automating Recovery Solutions for Patients
The continuous renal replacement therapy landscape is moderately consolidated. That is why it is important for existing and emerging market players to develop effective alternatives to certain limitations of therapies. For instance, technical limitations of the equipment supporting continuous renal replacement therapy are related to the software for hemodynamic optimization. As such, there is a growing need for continuous evaluation of the effectiveness for solute and fluid removal in continuous renal replacement therapies, and for the efficient management of big amounts of data in software systems. Technical improvements of dynamic CRRT and the availability of online tools for real-time data acquisition in software systems will help nephrologists evaluate whether the prescribed treatment has been effective in patients.
Another challenge arises from dialysis devices that require smart dialysis software to deliver automatic ‘smart’ decisions. As such, manufacturers are developing expert decision support systems that infer upon previous experiences of patients to solve problems.
Analysts’ Viewpoint
Incorporation of nanotechnology, sorbent-based techniques, and water-saving strategies are the key trends in the continuous renal replacement therapy ecosystem. Nanotechnology is anticipated to enhance the portability of future devices. Due to the constant need for effective follow-up in patients, manufacturers are innovating on AI (Artificial Intelligence) technology and sensing, which can be used in ICUs to predict which patients are at high risk of imminent deterioration. However, AI technologies face challenges due to the lack of privacy and consent to acquire population-derived datasets to be made available for large private prospectors. Thus, manufacturers should focus on ‘computational thinking’ that helps analyze patterns in the clinical status of a patient, based on algorithms.
Global Continuous Renal Replacement Therapy Market: Overview
The global continuous renal replacement therapy (CRRT) market was valued at ~US$ 865 Mn in 2018. It is projected to expand at a high CAGR of ~7% from 2019 to 2027.
Rise in acute kidney injury diseases, increase in patient pool, advancements in technology, growth in the geriatric population, surge in investments, and rising number of dialysis centers are likely to fuel the growth of the global continuous renal replacement therapy market.
Continuous renal replacement therapy is used to treat acute kidney injury of hospitalized, critically-ill patients admitted in an ICU. Continuous renal replacement therapy is a preferred modality for managing the hemodynamic status of patients suffering from acute kidney injury.
Patients with acute renal failure and those experiencing complications such as imperfections or multiple organ failure in their circulatory systems, or cardiac that includes edema and cardiac insufficiency, are also treated using CRRT systems. Other complications where CRRT systems are used include postoperative liver failure, fulminant hepatitis, serve acute pancreatitis, and multiple organ failure.
Increase in the rate of incidences of acute kidney injury, growing geriatric population with comorbidities, government focus on providing better healthcare facilities, rise in the prevalence of diabetes and hypertension associated with acute kidney injury, and increasing dialysis centers are expected to boost the global continuous renal replacement therapy market. As per research, 13.2 million people are affected with acute kidney injury globally each year, and acute kidney injury affects 13% to 18% of all patients admitted in hospitals in developed countries. These factors are expected to fuel the adoption of continuous dialysis for optimum care of patients.
Technological advancements are leading to the integration of new software to enhance continuous renal replacement treatment. Software integration has become an efficient tool for performing the treatment efficiently and accurately. Moreover, the acquisition of R&D units of emerging players to co-develop innovative technologies is anticipated to offer growth opportunities in the market.
Global Continuous Renal Replacement Therapy Market: Segment Analysis
The global continuous renal replacement therapy market has been segmented based on mode, product, therapy, end user, and region
Based on mode, the global continuous renal replacement therapy market has been categorized into slow continuous ultrafiltration (SCUF), continuous venovenous haemofiltration (CVVH), continuous venovenous haemodialysis (CVVHD), and continuous venovenous haemodiafiltration (CVVHDF). Among these, the continuous venovenous haemofiltration segment is projected to lead the global continuous renal replacement therapy market during the forecast period. The high market share of the continuous venovenous haemofiltration segment can be attributed to the acceptance of this technology by nephrologists, as it is more feasible than the other modes. This technology also incurs less complications than the other modes.
In terms of product, the global continuous renal replacement therapy market has been divided into dialysate & replacement fluids, disposables, and systems. The disposables segment is further classified into bloodline sets, hemofilters, and other disposables. The disposables segment is likely to dominate the global CRRT market, owing to the high volume sales of disposables and optimal usage of bloodline sets, hemofilters, and tubing in continuous dialysis procedures. The hemofilters sub-segment held the largest share of the disposables segment in 2018, and is expected to continue its dominance in the coming years.
On the basis of therapy, the global continuous renal replacement therapy market has been segmented into renal, non-renal, and combination. The renal segment accounted for the largest share of the global continuous renal replacement therapy market, and is expected to continue its dominance, owing to the optimum usage of CRRT machines for renal indication and availability of CRRT modalities. The combination segment is anticipated to grow at the highest rate, owing to a rise in the global geriatric population facing the risk of developing both, renal and non-renal indications.
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Based on end user, the global continuous renal replacement therapy market has been classified into hospitals, clinics, and others. The hospitals segment dominated the global CRRT market in 2018, owing to well-established intensive care units in hospitals across the globe.
Global Continuous Renal Replacement Therapy Market: Regional Segmentation
In terms of region, the global continuous renal replacement therapy market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa
Europe dominated the global continuous renal replacement therapy market in 2018, owing to increase in incidences of acute kidney injury and favorable reimbursement policies. Moreover, the presence of key players in the region is driving the global continuous renal replacement therapy market. Well-established research & development industry, along with strong funding from governments for continuous renal replacement therapy in critically-ill patients is likely to boost market growth in the region.
The global continuous renal replacement therapy market in Asia Pacific is projected to expand at the highest CAGR during the forecast period, due to strong economic growth, rise in healthcare infrastructure, increase in geriatric population, and surge in investments for developing advanced CRRT products.
Initiatives by the local governments of countries in the region to attain self-sufficiency in manufacturing renal replacement devices are likely to propel the growth of the CRRT markets in Middle East & Africa and Latin America.
Global Continuous Renal Replacement Therapy Market: Major Players
Key players operating in the global continuous renal replacement therapy market include
- Baxter International, Inc.
- Nipro Corporation
- Fresenius Medical Care AG & Co. KGaA
- Asahi Kasei Corporation
- B. Braun Melsungen AG
- Medica SPA
- INFOMED SA
- Medtronic (Bellco Società unipersonale a r.l.)
- Toray Medical Company Limited (Toray Industries, Inc.)
These players are focused on adopting organic and inorganic growth strategies to strengthen their product portfolios to improve patient healthcare. Companies are focusing on increasing their geographical footprint, indulging in mergers & acquisitions, and investing in research & development in order to remain competitive in the global continuous renal replacement therapy market.
Key Questions Answered in the Continuous Renal Replacement Therapy Market Report
- How do recent technical advancements provide scope of growth in the global continuous renal replacement therapy market?
- How are mergers & acquisitions among players widening the scope for continuous renal replacement therapy?
- What are the revenue share projections of key segments under various criteria in the global continuous renal replacement therapy market during the forecast period?
- Which segment is likely to lead the continuous renal replacement therapy market in terms of revenue by 2027?
- How are changing reimbursement and regulatory scenarios, along with changing healthcare systems in developing countries making an impact on the global CRRT market?
Continuous Renal Replacement Therapy Market – Segmentation
Mode
- Slow Continuous Ultrafiltration (SCUF)
- Continuous Venovenous Haemofiltration (CVVHF)
- Continuous Venovenous Haemodialysis (CVVHD)
- Continuous Venovenous Haemodiafiltration(CVVHDF)
Product
- Dialysate & Replacement Fluids
- Disposables
- Bloodline Sets
- Hemofilters
- Other Disposables
- Systems
Therapy
- Renal
- Non-renal
- Combination
End User
- Hospitals
- Clinics
- Others
Region
- North America
- Europe
- Asia Pacific
- Latin America
- Middle East & Africa
TABLE OF CONTENT
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary : Global Continuous Renal Replacement Therapy Market
4. Market Overview
4.1. Introduction
4.1.1. Market Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Continuous Renal Replacement Therapy Market Analysis Forecast, 2017–2027
4.4.1. Market Revenue Projection (US$ Mn)
5. Market Outlook
5.1. Incidence of Acute Kidney Injury Across the Globe
5.2. Rise in Prevalence of Diabetes and Hypertension
5.3. Reimbursement Scenario by Region/globally
5.4. Regulatory Scenario by Region/globally
5.5. Recent Technological Developments in Continuous Renal Replacement Therapy
5.6. Development of CRRT System for Paediatric Patients
5.7. Key Mergers & Acquisitions
6. Global Continuous Renal Replacement Therapy Market Analysis Forecast, by Mode
6.1. Introduction & Definition
6.2. Key Findings / Developments
6.3. Global Continuous Renal Replacement Therapy Market Value (US$) Forecast, by Mode, 2017–2027
6.3.1. Slow Continuous Ultrafiltration (SCUF)
6.3.2. Continuous VenoVenous Haemofiltration (CVVHF)
6.3.3. Continuous VenoVenous Haemodialysis (CVVHD)
6.3.4. Continuous VenoVenous Haemodiafiltration (CVVHDF)
6.4. Continuous Renal Replacement Therapy Market Attractiveness, by Mode
7. Global Continuous Renal Replacement Therapy Market Analysis Forecast, by Product
7.1. Introduction & Definition
7.2. Key Findings / Developments
7.3. Continuous Renal Replacement Therapy Market Value Forecast, by Product, 2017–2027
7.3.1. Dialysate & Replacement Fluids
7.3.2. Disposables
7.3.2.1. Bloodline Sets
7.3.2.2. Hemofilters
7.3.2.3. Other Disposables
7.3.3. Systems
7.4. Continuous Renal Replacement Therapy Market Attractiveness, by Product
8. Global Continuous Renal Replacement Therapy Market Analysis Forecast, by Therapy
8.1. Introduction & Definition
8.2. Key Findings / Developments
8.3. Continuous Renal Replacement Therapy Market Value Forecast, by Therapy , 2017–2027
8.3.1. Renal
8.3.2. Non-renal
8.3.3. Combination
8.4. Continuous Renal Replacement Therapy Market Attractiveness, by Therapy
9. Global Continuous Renal Replacement Therapy Market Analysis Forecast, by End-user
9.1. Introduction & Definition
9.2. Key Findings / Developments
9.3. Continuous Renal Replacement Therapy Market Value Forecast, by End-user , 2017–2027
9.3.1. Hospitals
9.3.2. Clinics
9.3.3. Others
9.4. Continuous Renal Replacement Therapy Market Attractiveness, by End-user
10. Global Continuous Renal Replacement Therapy Market Analysis Forecast, by Region
10.1. Key Findings
10.2. Continuous Renal Replacement Therapy Market Value Forecast, by Region
10.2.1. North America
10.2.2. Europe
10.2.3. Asia Pacific
10.2.4. Latin America
10.2.5. Middle East & Africa
10.3. Continuous Renal Replacement Therapy Market Attractiveness, by Country/Region
11. North America Continuous Renal Replacement Therapy Market Analysis
11.1. Introduction
11.1.1. Key Findings
11.2. North America Continuous Renal Replacement Therapy Market Value Forecast, by Mode, 2017–2027
11.2.1. Slow Continuous Ultrafiltration (SCUF)
11.2.2. Continuous Venovenous Haemofiltration (CVVHF)
11.2.3. Continuous Venovenous Haemodialysis (CVVHD)
11.2.4. Continuous Venovenous Haemodiafiltration (CVVHDF)
11.3. North America Continuous Renal Replacement Therapy Market Value Forecast, by Product, 2017–2027
11.3.1. Dialysate & Replacement Fluids
11.3.2. Disposables
11.3.2.1. Bloodline Sets
11.3.2.2. Hemofilters
11.3.2.3. Other Disposables
11.3.3. Systems
11.4. North America Continuous Renal Replacement Therapy Market Value Forecast, by Therapy , 2017–2027
11.4.1. Renal
11.4.2. Non-renal
11.4.3. Combination
11.5. North America Continuous Renal Replacement Therapy Market Value Forecast, by End-user , 2017–2027
11.5.1. Hospitals
11.5.2. Clinics
11.5.3. Others
11.6. North America Continuous Renal Replacement Therapy Market Value Forecast, by Country, 2017–2027
11.6.1. U.S.
11.6.2. Canada
11.7. North America Continuous Renal Replacement Therapy Market Attractiveness Analysis
11.7.1. By Mode
11.7.2. By Product
11.7.3. By Therapy
11.7.4. By End-user
11.7.5. By Country
12. Europe Continuous Renal Replacement Therapy Market Analysis
12.1. Introduction
12.1.1. Key Findings
12.2. Europe Continuous Renal Replacement Therapy Market Value Forecast, by Mode, 2017–2027
12.2.1. Slow Continuous Ultrafiltration (SCUF)
12.2.2. Continuous Venovenous Haemofiltration (CVVHF)
12.2.3. Continuous Venovenous Haemodialysis (CVVHD)
12.2.4. Continuous Venovenous Haemodiafiltration (CVVHDF)
12.3. Europe Continuous Renal Replacement Therapy Market Value Forecast, by Product, 2017–2027
12.3.1. Dialysate & Replacement Fluids
12.3.2. Disposables
12.3.2.1. Bloodline Sets
12.3.2.2. Hemofilters
12.3.2.3. Other Disposables
12.3.3. Systems
12.4. Europe Continuous Renal Replacement Therapy Market Value Forecast, by Therapy , 2017–2027
12.4.1. Renal
12.4.2. Non-renal
12.4.3. Combination
12.5. Europe Continuous Renal Replacement Therapy Market Value Forecast, by End-user , 2017–2027
12.5.1. Hospitals
12.5.2. Clinics
12.5.3. Others
12.6. Europe Continuous Renal Replacement Therapy Market Value Forecast, by Country, 2017–2027
12.6.1. Germany
12.6.2. U.K.
12.6.3. France
12.6.4. Spain
12.6.5. Italy
12.6.6. Rest of Europe
12.7. Europe Continuous Renal Replacement Therapy Market Attractiveness Analysis
12.7.1. By Mode
12.7.2. By Product
12.7.3. By Therapy
12.7.4. By End-user
12.7.5. By Country
13. Asia-Pacific Continuous Renal Replacement Therapy Market Analysis
13.1. Introduction
13.1.1. Key Findings
13.2. Asia-Pacific Continuous Renal Replacement Therapy Market Value Forecast, by Mode, 2017–2027
13.2.1. Slow Continuous Ultrafiltration (SCUF)
13.2.2. Continuous Venovenous Haemofiltration (CVVHF)
13.2.3. Continuous Venovenous Haemodialysis (CVVHD)
13.2.4. Continuous Venovenous Haemodiafiltration (CVVHDF)
13.3. Asia-Pacific Continuous Renal Replacement Therapy Market Value Forecast, by Product, 2017–2027
13.3.1. Dialysate & Replacement Fluids
13.3.2. Disposables
13.3.2.1. Bloodline Sets
13.3.2.2. Hemofilters
13.3.2.3. Other Disposables
13.3.3. Systems
13.4. Asia-Pacific Continuous Renal Replacement Therapy Market Value Forecast, by Therapy , 2017–2027
13.4.1. Renal
13.4.2. Non-renal
13.4.3. Combination
13.5. Asia-Pacific Continuous Renal Replacement Therapy Market Value Forecast, by End-user , 2017–2027
13.5.1. Hospitals
13.5.2. Clinics
13.5.3. Others
13.6. Asia-Pacific Continuous Renal Replacement Therapy Market Value Forecast, by Country, 2017–2027
13.6.1. China
13.6.2. Japan
13.6.3. India
13.6.4. Australia & New Zealand
13.6.5. Rest of Asia Pacific
13.7. Asia-Pacific Continuous Renal Replacement Therapy Market Attractiveness Analysis
13.7.1. By Mode
13.7.2. By Product
13.7.3. By Therapy
13.7.4. By End-user
13.7.5. By Country
14. Latin America Continuous Renal Replacement Therapy Market Analysis
14.1. Introduction
14.1.1. Key Findings
14.2. Latin America Continuous Renal Replacement Therapy Market Value Forecast, by Mode, 2017–2027
14.2.1. Slow Continuous Ultrafiltration (SCUF)
14.2.2. Continuous Venovenous Haemofiltration (CVVHF)
14.2.3. Continuous Venovenous Haemodialysis (CVVHD)
14.2.4. Continuous Venovenous Haemodiafiltration (CVVHDF)
14.3. Latin America Continuous Renal Replacement Therapy Market Value Forecast, by Product, 2017–2027
14.3.1. Dialysate & Replacement Fluids
14.3.2. Disposables
14.3.2.1. Bloodline Sets
14.3.2.2. Hemofilters
14.3.2.3. Other Disposables
14.3.3. Systems
14.4. Latin America Continuous Renal Replacement Therapy Market Value Forecast, by Therapy , 2017–2027
14.4.1. Renal
14.4.2. Non-renal
14.4.3. Combination
14.5. Latin America Continuous Renal Replacement Therapy Market Value Forecast, by End-user , 2017–2027
14.5.1. Hospitals
14.5.2. Clinics
14.5.3. Others
14.6. Latin America Continuous Renal Replacement Therapy Market Value Forecast, by Country, 2017–2027
14.6.1. Brazil
14.6.2. Mexico
14.6.3. Rest of Latin America
14.7. Latin America Continuous Renal Replacement Therapy Market Attractiveness Analysis
14.7.1. By Mode
14.7.2. By Product
14.7.3. By Therapy
14.7.4. By End-user
14.7.5. By Country
15. Middle East & Africa Continuous Renal Replacement Therapy Market Analysis
15.1. Introduction
15.1.1. Key Findings
15.2. Middle East & Africa Continuous Renal Replacement Therapy Market Value Forecast, by Mode, 2017–2027
15.2.1. Slow Continuous Ultrafiltration (SCUF)
15.2.2. Continuous Venovenous Haemofiltration (CVVHF)
15.2.3. Continuous Venovenous Haemodialysis (CVVHD)
15.2.4. Continuous Venovenous Haemodiafiltration (CVVHDF)
15.3. Middle East & Africa Continuous Renal Replacement Therapy Market Value Forecast, by Product, 2017–2027
15.3.1. Dialysate & Replacement Fluids
15.3.2. Disposables
15.3.2.1. Bloodline Sets
15.3.2.2. Hemofilters
15.3.2.3. Other Disposables
15.3.3. Systems
15.4. Middle East & Africa Continuous Renal Replacement Therapy Market Value Forecast, by Therapy , 2017–2027
15.4.1. Renal
15.4.2. Non-renal
15.4.3. Combination
15.5. Middle East & Africa Continuous Renal Replacement Therapy Market Value Forecast, by End-user , 2017–2027
15.5.1. Hospitals
15.5.2. Clinics
15.5.3. Others
15.6. Middle East & Africa Continuous Renal Replacement Therapy Market Value Forecast, by Country, 2017–2027
15.6.1. GCC Countries
15.6.2. South Africa
15.6.3. Rest of Middle East & Africa
15.7. Middle East & Africa Continuous Renal Replacement Therapy Market Attractiveness Analysis
15.7.1. By Mode
15.7.2. By Product
15.7.3. By Therapy
15.7.4. By End-user
15.7.5. By Country
16. Competition Landscape
16.1. Market Player – Competition Matrix (By Tier and Size of companies)
16.2. Market Position By Company (2018)
16.3. Company Profiles
16.3.1. Baxter International, Inc
16.3.1.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.1.2. Financial Overview
16.3.1.3. Product Portfolio
16.3.1.4. Strategic Overview
16.3.1.5. SWOT Analysis
16.3.2. Nipro Corporation
16.3.2.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.2.2. Financial Overview
16.3.2.3. Product Portfolio
16.3.2.4. Strategic Overview
16.3.2.5. SWOT Analysis
16.3.3. Fresenius Medical Care AG & Co. KGaA
16.3.3.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.3.2. Financial Overview
16.3.3.3. Product Portfolio
16.3.3.4. Strategic Overview
16.3.3.5. SWOT Analysis
16.3.4. Asahi Kasei Corporation
16.3.4.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.4.2. Financial Overview
16.3.4.3. Product Portfolio
16.3.4.4. Strategic Overview
16.3.4.5. SWOT Analysis
16.3.5. B. Braun Melsungen AG
16.3.5.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.5.2. Financial Overview
16.3.5.3. Product Portfolio
16.3.5.4. Strategic Overview
16.3.5.5. SWOT Analysis
16.3.6. NIKKISO CO., LTD
16.3.6.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.6.2. Financial Overview
16.3.6.3. Product Portfolio
16.3.6.4. Strategic Overview
16.3.6.5. SWOT Analysis
16.3.7. Medica SPA
16.3.7.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.7.2. Product Portfolio
16.3.7.3. Strategic Overview
16.3.7.4. SWOT Analysis
16.3.8. INFOMED SA
16.3.8.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.8.2. Product Portfolio
16.3.8.3. Strategic Overview
16.3.8.4. SWOT Analysis
16.3.9. Medtronic (Bellco Società unipersonale a r.l.)
16.3.9.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.9.2. Financial Overview
16.3.9.3. Product Portfolio
16.3.9.4. Strategic Overview
16.3.9.5. SWOT Analysis
16.3.10. Toray Medical Company Limited (Toray Industries, Inc.)
16.3.10.1. Company Overview (HQ, Business Segments, Employee Strength)
16.3.10.2. Product Portfolio
16.3.10.3. Strategic Overview
16.3.10.4. SWOT Analysis
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