Lyophilized Injectable Market Size to Worth Around USD 5 Bn by 2030

The worldwide Lyophilized Injectable market measurement is anticipated to achieve USD 5 billion by 2030 and is anticipated to increase at a CAGR of 5.1% from 2021 to 2030.

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Lyophilization is the most commonly used method for the manufacturing of parenteral pharmaceutical products, when the product is unstable in aqueous solution. It is central to the protection of materials, which require low moisture content (less than 1%) in order to ensure stability and require a sterile and gentle preservation process.

Improved quality and shelf life of lyophilized drugs has attracted industry experts to implement lyophilization in their manufacturing processes. Contract research and manufacturing organizations have increased the use of lyophilized injectable drugs to provide quality products to customers. Therefore, rapidly growing contract research manufacturing services (CRAMS) is projected to drive the global lyophilized injectable market.

Lyophilized injectable drugs are stable at ambient temperatures and only require simple rehydration to be ready to use. This removes many sources of pipetting errors, while streamlining and simplifying workflows.

Elimination of the cold chain minimizes costs and carbon footprint, and provides a positive environmental impact by minimizing the need of expanded polystyrene (EPS or ‘Styrofoam’) containers often utilized to ship temperature-controlled products.

Lyophilized products are considered safe for use, while delivering the desired functionality compared to non-lyophilized products. Moreover, lyophilization helps retain the biological and chemical activity of the chemical compound in the final product. This drives the demand for lyophilized injectable drugs in the pharmaceutical and biotechnology industries.

Expansion of Pipeline of Lyophilized Injectable Drugs to Drive Global Market

The continuous research & development to develop innovative drugs for the treatment of chronic diseases has propelled the development of lyophilized injectable drugs in the pharmaceutical industry. Product innovation and acquisition provide key players with the opportunities to penetrate a new therapeutic area/market. About 2,400 injectable products are presently in the development pipeline. This is expected to augment the global lyophilized injectable market.

Development of Alternative Methods to Hamper Market Growth

Lyophilization of injectable drugs is an expensive process. Hence, manufacturers strive to develop alternative drying methods to increase the shelf life of products, which can prove economical. However, such alternative processes need improvement in terms of retaining stability and biological or chemical activity of the substance. Roche has developed a precipitation method as an alternative to lyophilization for the production of peptides, which enabled the company to reduce production costs, and deliver an effective, quality, and affordable product to customers. The advent of alternative methods during the forecast period is likely to hamper the growth of the global lyophilized injectable market.

Single-use Vials Dominated Global Market

The report offers detailed segmentation of the global lyophilized injectable market based on type of packaging, type of delivery, indication, and end user. In terms of type of packaging, the single-use vials segment dominated the global market in 2020. The increase in self-administration of lyophilized injectable drugs to treat various chronic conditions such as diabetes, rheumatoid arthritis, and migraine is projected to drive the single-use vials segment during the forecast period. The specialty packaging segment is expected to grow at a rapid pace from 2021 to 2031, as the segment offers packaging solutions such as pens, needle-free injectors, and two-part syringes that allow reconstitution in the device prior to injection.

Hospitals to be Major End User

In terms of end user, the lyophilized injectable market has been divided into hospitals, ambulatory surgical centers, specialty clinics, and others The hospitals segment is expected to expand at a high CAGR during the forecast period, due to increase in the number of hospitals and high patient preference to visit hospitals for treatment.

North America to Dominate Global Market

The global lyophilized injectable market has been segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominated the global lyophilized injectable market in 2020, followed by Europe. North America accounted for a major share of the global lyophilized injectable market in 2020, due to extensive research & development activities, rapid acceptance of innovative technologies, and significant investments toward the development of healthcare infrastructure. Additionally, presence of a large number of manufacturing facilities in North America makes it the largest market for lyophilized injectable drugs.

Competitive Landscape and Market Share Analysis

The lyophilized injectable market competitive landscape provides details by vendors, including company overview, company total revenue (financials), market potential, global presence, lyophilized injectable sales and revenue generated, market share, price, production sites and facilities, SWOT analysis, product launch. For the period 2017-2020, this study provides the lyophilized injectable sales, revenue and market share for each player covered in this report.

  • Crucial data regarding the major contenders, product portfolio, market remuneration, and production patterns are documented in the report.
  • The report presents the pricing models followed by each company, alongside the gross margins and market share held by each company.

The report also presents profiles of leading players in the global lyophilized injectable market. These include B. Braun Melsungen AG, Baxter International, Inc., BD, Schott AG, Aristopharma Ltd., Vetter Pharma, and Jubilant HollisterStier LLC.

Market Segmentation

Market By Type of Packaging

    • Single-use Vials
    • Point-of-care Reconstitution
    • Specialty Packaging

Market By Type of Delivery

    • Prefilled Diluent Syringes
    • Proprietary Reconstitution Devices
    • Single-step Devices
    • Multi-step Devices

Market By Indication

    • Autoimmune Diseases
    • Metabolic Conditions
    • Infectious Diseases
    • Others

Market By End User

    • Hospitals
    • Ambulatory Surgical Centers
    • Specialty Clinics
    • Others

Market By Region

    • North America
      • U.S.
      • Canada
    • Europe
      • Germany
      • U.K.
      • France
      • Italy
      • Spain
      • Rest of Europe
    • Asia Pacific
      • China
      • India
      • Japan
      • Australia & New Zealand
      • Rest of Asia Pacific
    • Latin America
      • Brazil
      • Mexico
      • Rest of Latin America
    • Middle East & Africa
      • GCC Countries
      • South Africa
      • Rest of Middle East & Africa

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Research Methodology

The research methodology adopted by analysts for compiling the global lyophilized injectable market report is based on detailed primary as well as secondary research. With the help of in-depth insights of the market-affiliated information that is obtained and legitimated by market-admissible resources, analysts have offered riveting observations and authentic forecasts for the global market.

During the primary research phase, analysts interviewed market stakeholders, investors, brand managers, vice presidents, and sales and marketing managers. Based on data obtained through interviews of genuine resources, analysts have emphasized the changing scenario of the global market.

For secondary research, analysts scrutinized numerous annual report publications, white papers, market association publications, and company websites to obtain the necessary understanding of the global lyophilized injectable market.

Table of Contents

Chapter 1.    Introduction

1.1.  Research Objective

1.2.  Scope of the Study

1.3.  Definition

Chapter 2.    Research Methodology

2.1.  Research Approach

2.2.  Data Sources

2.3.  Assumptions & Limitations

Chapter 3.    Executive Summary

3.1.  Market Snapshot

Chapter 4.    Market Variables and Scope

4.1.  Introduction

4.2.  Market Classification and Scope

4.3.  Industry Value Chain Analysis

4.3.1.     Raw Material Procurement Analysis

4.3.2.     Sales and Distribution Channel Analysis

4.3.3.     Downstream Buyer Analysis

Chapter 5.    Market Dynamics Analysis and Trends

5.1.  Market Dynamics

5.1.1.     Market Drivers

5.1.2.     Market Restraints

5.1.3.     Market Opportunities

5.2.  Porter’s Five Forces Analysis

5.2.1.     Bargaining power of suppliers

5.2.2.     Bargaining power of buyers

5.2.3.     Threat of substitute

5.2.4.     Threat of new entrants

5.2.5.     Degree of competition

Chapter 6.    Competitive Landscape

6.1.1.     Company Market Share/Positioning Analysis

6.1.2.     Key Strategies Adopted by Players

6.1.3.     Vendor Landscape

6.1.3.1.          List of Suppliers

6.1.3.2.          List of Buyers

Chapter 7.    Global Lyophilized Injectable Market, By Type of Packaging

7.1.  Lyophilized Injectable Market, by Type of Packaging, 2021-2030

7.1.1.     Single-use Vials

7.1.1.1.          Market Revenue and Forecast (2016-2030)

7.1.2.     Point-of-care Reconstitution

7.1.2.1.          Market Revenue and Forecast (2016-2030)

7.1.3.     Specialty Packaging

7.1.3.1.          Market Revenue and Forecast (2016-2030)

Chapter 8.    Global Lyophilized Injectable Market, By Type of Delivery

8.1.  Lyophilized Injectable Market, by Type of Delivery, 2021-2030

8.1.1.     Prefilled Diluent Syringes

8.1.1.1.          Market Revenue and Forecast (2016-2030)

8.1.2.     Proprietary Reconstitution Devices

8.1.2.1.          Market Revenue and Forecast (2016-2030)

8.1.3.     Single-step Devices

8.1.3.1.          Market Revenue and Forecast (2016-2030)

8.1.4.     Multi-step Devices

8.1.4.1.          Market Revenue and Forecast (2016-2030)

Chapter 9.    Global Lyophilized Injectable Market, By Indication

9.1.  Lyophilized Injectable Market, by Indication, 2021-2030

9.1.1.     Autoimmune Diseases

9.1.1.1.          Market Revenue and Forecast (2016-2030)

9.1.2.     Metabolic Conditions

9.1.2.1.          Market Revenue and Forecast (2016-2030)

9.1.3.     Infectious Diseases

9.1.3.1.          Market Revenue and Forecast (2016-2030)

9.1.4.     Others

9.1.4.1.          Market Revenue and Forecast (2016-2030)

Chapter 10.Global Lyophilized Injectable Market, By End User

10.1.          Lyophilized Injectable Market, by End User, 2021-2030

10.1.1.  Hospitals

10.1.1.1.       Market Revenue and Forecast (2016-2030)

10.1.2.  Ambulatory Surgical Centers

10.1.2.1.       Market Revenue and Forecast (2016-2030)

10.1.3.  Specialty Clinics

10.1.3.1.       Market Revenue and Forecast (2016-2030)

10.1.4.  Others

10.1.4.1.       Market Revenue and Forecast (2016-2030)

Chapter 11.Global Lyophilized Injectable Market, Regional Estimates and Trend Forecast

11.1.          North America

11.1.1.  Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.1.2.  Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.1.3.  Market Revenue and Forecast, by Indication (2016-2030)

11.1.4.  Market Revenue and Forecast, by End User (2016-2030)

11.1.5.  U.S.

11.1.5.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.1.5.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.1.5.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.1.5.4.       Market Revenue and Forecast, by End User (2016-2030)

11.1.6.  Rest of North America

11.1.6.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.1.6.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.1.6.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.1.6.4.       Market Revenue and Forecast, by End User (2016-2030)

11.2.          Europe

11.2.1.  Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.2.2.  Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.2.3.  Market Revenue and Forecast, by Indication (2016-2030)

11.2.4.  Market Revenue and Forecast, by End User (2016-2030)

11.2.5.  UK

11.2.5.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.2.5.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.2.5.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.2.5.4.       Market Revenue and Forecast, by End User (2016-2030)

11.2.6.  Germany

11.2.6.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.2.6.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.2.6.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.2.6.4.       Market Revenue and Forecast, by End User (2016-2030)

11.2.7.  France

11.2.7.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.2.7.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.2.7.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.2.7.4.       Market Revenue and Forecast, by End User (2016-2030)

11.2.8.  Rest of Europe

11.2.8.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.2.8.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.2.8.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.2.8.4.       Market Revenue and Forecast, by End User (2016-2030)

11.3.          APAC

11.3.1.  Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.3.2.  Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.3.3.  Market Revenue and Forecast, by Indication (2016-2030)

11.3.4.  Market Revenue and Forecast, by End User (2016-2030)

11.3.5.  India

11.3.5.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.3.5.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.3.5.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.3.5.4.       Market Revenue and Forecast, by End User (2016-2030)

11.3.6.  China

11.3.6.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.3.6.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.3.6.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.3.6.4.       Market Revenue and Forecast, by End User (2016-2030)

11.3.7.  Japan

11.3.7.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.3.7.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.3.7.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.3.7.4.       Market Revenue and Forecast, by End User (2016-2030)

11.3.8.  Rest of APAC

11.3.8.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.3.8.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.3.8.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.3.8.4.       Market Revenue and Forecast, by End User (2016-2030)

11.4.          MEA

11.4.1.  Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.4.2.  Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.4.3.  Market Revenue and Forecast, by Indication (2016-2030)

11.4.4.  Market Revenue and Forecast, by End User (2016-2030)

11.4.5.  GCC

11.4.5.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.4.5.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.4.5.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.4.5.4.       Market Revenue and Forecast, by End User (2016-2030)

11.4.6.  North Africa

11.4.6.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.4.6.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.4.6.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.4.6.4.       Market Revenue and Forecast, by End User (2016-2030)

11.4.7.  South Africa

11.4.7.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.4.7.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.4.7.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.4.7.4.       Market Revenue and Forecast, by End User (2016-2030)

11.4.8.  Rest of MEA

11.4.8.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.4.8.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.4.8.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.4.8.4.       Market Revenue and Forecast, by End User (2016-2030)

11.5.          Latin America

11.5.1.  Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.5.2.  Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.5.3.  Market Revenue and Forecast, by Indication (2016-2030)

11.5.4.  Market Revenue and Forecast, by End User (2016-2030)

11.5.5.  Brazil

11.5.5.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.5.5.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.5.5.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.5.5.4.       Market Revenue and Forecast, by End User (2016-2030)

11.5.6.  Rest of LATAM

11.5.6.1.       Market Revenue and Forecast, by Type of Packaging (2016-2030)

11.5.6.2.       Market Revenue and Forecast, by Type of Delivery (2016-2030)

11.5.6.3.       Market Revenue and Forecast, by Indication (2016-2030)

11.5.6.4.       Market Revenue and Forecast, by End User (2016-2030)

Chapter 12.   Company Profiles

12.1.                 B. Braun Melsungen AG

12.1.1.  Company Overview

12.1.2.  Product Offerings

12.1.3.  Financial Performance

12.1.4.  Recent Initiatives

12.2.                 Baxter International Inc

12.2.1.  Company Overview

12.2.2.  Product Offerings

12.2.3.  Financial Performance

12.2.4.  Recent Initiatives

12.3.                 BD

12.3.1.  Company Overview

12.3.2.  Product Offerings

12.3.3.  Financial Performance

12.3.4.  Recent Initiatives

12.4.                 Schott AG

12.4.1.  Company Overview

12.4.2.  Product Offerings

12.4.3.  Financial Performance

12.4.4.  Recent Initiatives

12.5.                 Aristopharma Ltd.

12.5.1.  Company Overview

12.5.2.  Product Offerings

12.5.3.  Financial Performance

12.5.4.  Recent Initiatives

12.6.                 Vetter Pharma

12.6.1.  Company Overview

12.6.2.  Product Offerings

12.6.3.  Financial Performance

12.6.4.  Recent Initiatives

12.7.                 Jubilant HollisterStier LLC.

12.7.1.  Company Overview

12.7.2.  Product Offerings

12.7.3.  Financial Performance

12.7.4.  Recent Initiatives

Chapter 13.   Research Methodology

13.1.                 Primary Research

13.2.                 Secondary Research

13.3.                 Assumptions

Chapter 14.   Appendix

14.1.                 About Us

14.2.                 Glossary of Terms

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