The global oligonucleotide synthesis market for the historical period 2017–2018 and forecast period 2019–2027, Increasing use of synthesized oligonucleotides in diagnostics and research applications, and Technological advancements in synthetic chemistry are projected to drive the global oligonucleotide synthesis market during the forecast period
According to the report, the global oligonucleotide synthesis market was valued at US$ 1,966.2 Mn in 2018 and is anticipated to expand at a CAGR of 9.5% from 2019 to 2030
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Technological advancements in synthetic chemistry to Drive Global Oligonucleotide Synthesis: Key Drivers
The advances in the technological development of organic molecules are expected to drive the growth of the oligonucleotide synthesis market
The advanced synthesis of oligonucleotides provides longer oligos with better sequence fidelity and higher purity that can be used in a number of molecular biology applications
Various pharmaceutical and biotechnology companies are continuously working on developing newer and advanced methods in synthetic chemistry
For instance, Integrated DNA Technologies, leader of synthesized oligonucleotides has developed various pioneered methods to synthesize oligonucleotides of extreme lengths. The company has developed oligonucleotides up to 200 base length which is used with mass spectrometry for the manufacture of mini-genes.
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Increasing use of Synthesized Oligonucleotides in Diagnostics and Research Applications Boost Market Growth
Oligonucleotides have a wide range of applications in areas such as molecular biology, biotechnology, and diagnosis
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Natural oligonucleotides have been extensively used for the selection and determination of DNA sequences (hybridization probes or affinity purification), gene construction, and site-directed mutagenesis
They constitute the basic reagents for PCR technologies. They are also used to selectively inhibit gene expression in in vitro studies for diagnostic purpose and more recently, their ability to interact with proteins has generated immense opportunity for therapeutic use.
Along with diagnostics, they are widely used in research studies. Combinatorial technology is another research area where oligonucleotides and their analogs are extensively employed.
Limitations in the Synthesis of Oligonucleotides to Hamper Market
An oligonucleotide is a single-stranded chain consisting of a number of nucleoside units linked together by phosphodiester bridges
Mostly in oligonucleotide synthesis, phosphodiesters are formed between a 3’-hydroxyl group bearing a phosphate derivative and a 5’-hydroxyl group of another nucleoside
The occurrence of side reactions sets practical limits for the length of synthetic DNA oligonucleotides (up to about 200 nucleotide residues) because the number of errors accumulates with the length of the oligonucleotide being synthesized
To synthesize RNA with longer nucleotides base, that is more than 50 nucleotides is very complex and difficult to prepare
But, most biologically important RNA molecules such as ribozymes, aptamers, and riboswitches are significantly longer than 50 nucleotides, so new approaches for the synthesis of RNA analogs are urgently required
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Global Oligonucleotide Synthesis Market: Competitive Landscape
This report profiles major players in the global oligonucleotide synthesis market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments
The global oligonucleotide synthesis market is highly fragmented, with the presence of a number of international as well as regional players
Leading players operating in the global Oligonucleotide Synthesis market are
- GE Healthcare
- Thermo Fischer Scientific
- Agilent Technologies, Inc.
- Merck KGaA
- Integrated DNA Technologies, Inc.
- Kaneka Eurogentec S.A
- Gene Design, Inc.
- Eurofins Genomics
- ATDBio, Ltd..
Global Oligonucleotide Synthesis Market: Key Developments
Key players in the global oligonucleotide synthesis market are engaged in regulatory approvals, technologically advanced products, launch of new products, and acquisition & collaborative agreements with other companies. These strategies are likely to fuel the growth of the global oligonucleotide synthesis market. A few expansion strategies adopted by players operating in the global oligonucleotide Synthesis market are:
In May 2017, GE Healthcare announced the launch of its Superdex 30 Increase, a new generation column resin for small-scale preparative purification and analysis, adding another product to the already existing wide portfolio of Superdex Increase family of SEC columns.
The report on the global oligonucleotide synthesis market discussed individual strategies, followed by company profiles of manufacturers of oligonucleotide synthesis. The competitive landscape section has been included in the report to provide readers with a dashboard view and a company market share analysis of key players operating in the global oligonucleotide synthesis market.
Key Questions Answered in Global Oligonucleotide Synthesis Market Report
- What is the scope of growth of product companies in the global oligonucleotide synthesis market?
- What will be the Y-o-Y growth of the global oligonucleotide synthesis market between 2019 and 2027?
- What is the influence of changing trends in technologies on the global oligonucleotide synthesis market?
- Will North America continue to be the most profitable market for oligonucleotide synthesis providers?
- Which factors are anticipated to hamper the growth of the global oligonucleotide synthesis market during the forecast period?
- Which are the leading companies in the global oligonucleotide synthesis market?
Global Oligonucleotide Synthesis Market – Segmentation
Product Product Type
- Reagents & Consumables
- Synthesized Oligonucleotides
- Polymerase Chain Reaction
- Next Generation Sequencing
- Antisense Oligonucleotides
- Nucleic Acid Aptamers
- Biotech & Pharma Companies
- Research Inst.
- Diagnostic Labs
- North America
- Asia Pacific
- Latin America
TABLE OF CONTENT
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Oligonucleotide Synthesis Market
4. Market Overview
4.1.1. Product Type Definition
4.1.2. Industry Evolution / Developments
4.3. Market Dynamics
4.4. Global Oligonucleotide Synthesis Market Analysis and Forecast, 2017–2027
4.4.1. Market Revenue Projections (US$ Mn)
5. Key Insights
5.1. Porter’s Five Force Analysis
5.2. Value Chain Analysis
5.3. Market Outlook
5.4. Applications of Oligonucleotides
5.5. PEST Analysis
5.6. Pipeline Analysis
6. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Product Type
6.1. Introduction & Definition
6.1.1. Key Findings / Developments
6.2. Global Oligonucleotide Synthesis Market Value Forecast, by Product Type, 2017–2027
6.2.1. Reagents & Consumables
6.2.3. Synthesized oligonucleotides
184.108.40.206. DNA Oligonucleotides
220.127.116.11. RNA Oligonucleotides
6.3. Global Oligonucleotide Synthesis Market Attractiveness, by Product Type
7. Global Oligonucleotide Synthesis Market Analysis and Forecast, by Application
7.1. Introduction & Definition
7.1.1. Key Findings / Developments
7.2. Global Oligonucleotide Synthesis Market Value Forecast, by Application, 2017–2027
18.104.22.168. Polymerase Chain Reaction
22.214.171.124. Next Generation Sequencing
126.96.36.199. Antisense Oligonucleotides
188.8.131.52. Nucleic Acid Aptamers
7.3. Global Oligonucleotide Synthesis Market Attractiveness, by Application
8. Global Oligonucleotide Synthesis Market Analysis and Forecast, by End-user
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