Placental Stem Cell Therapy Market Perspective with Professional Survey & Competitive Dynamics till 2022-2030
Placental Stem Cell Therapy Holds Promising Potentials in Treatment of Coronavirus
The placental mesenchymal stem cells therapy is gaining popularity as a potential solution for the treatment of severe COVID-19. The Institute of Cell Therapy is acquiring recognition for successfully curing COVID-19 patients with the help of placental stem cells lacking ACE-2 receptor, which hold promising potentials in the treatment of coronavirus pneumonia. As such, worldwide inoculation of coronavirus vaccines from India has caused a slowdown in research activities of the placental stem cell therapy market.
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Stakeholders in the placental stem cell therapy market are anticipated to continue their research for minimizing the impacts of future coronavirus-like outbreaks. They are boosting clinical trials to evaluate the efficacy of stem cells of different types for the treatment of COVID-19 in China.
Robust Analytics, Independent Measurement Systems Improve Consistency in Production
The placental stem cell therapy market stood at US$ 0.5 Bn in 2019 and is expected to cross a revenue of US$ 4.4 Bn by the end of 2030. However, manufacturing is a consistent challenge for stem cell companies across various industries such as for neurological disorders, hematologic malignancies, and congenital immunodeficiency disorders. Hence, companies are mastering batch-to-batch consistency of C to monitor results.
Companies in the placental stem cell therapy market are focusing on producing cells in a consistent and quality manner. ReNeuron – a developer of therapeutics from retina specific stem cells is increasing efforts to strike the right balance between science and art to maintain consistency in cell production for the treatment of retinitis pigmentosa (RP).
MSC-based Therapies Help in Treatment of Respiratory Diseases
Mesenchymal stromal cell (MSC)-based therapies are appearing as new therapeutic strategies for lung diseases. Idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and acute respiratory distress syndrome (ARDS), among others, have triggered the demand for mesenchymal stromal cell-based therapies. MSCs are being publicized as multipotent cells with immune modulatory and regenerative properties. This explains why the placental stem cell therapy market is estimated to progress at an astonishing CAGR of 20% during the assessment period.
The acute respiratory distress syndrome is emerging as an ideal target for the mesenchymal stromal cell-based therapy, since MSCs act as immunomodulatory cells via rapid-acting paracrine effects. Companies in the placental stem cell therapy market are increasing efforts to conduct pre-clinical studies that demonstrate the efficacy of MSCs for ARDS.
Hepatocytes Generated from Stem Cells Show Potential in Treatment of Congenital Metabolic Diseases
Since congenital metabolic diseases are associated with morbidity due to invasive procedures such as liver transplant, healthcare companies in the placental stem cell therapy market are capitalizing on this opportunity to offer regenerative cell therapies. Regenerative therapy using hepatocytes generated from stem cells has the potential to treat congenital metabolic diseases. This technique is gaining popularity as a less invasive cell replacement approach, suitable for the treatment of congenital metabolic diseases.
Embryonic stem cells are prone to risks of tumorigenicity and difficulties with cell expansion, owing to the number needed for the anticipated therapeutic effect. Human amniotic epithelial cells (hAECs) have caught the attention of companies in the placental stem cell therapy market to treat congenital metabolic diseases.
Combined Transplantation of Allogeneic Stem Cells Being Used to Cure Neurological Diseases
Cell therapy of neurological diseases is gaining momentum in the placental stem cell therapy market. Stem and progenitor cells are showing positive therapeutic results in animal models of neurological disorders within clinical trials. It has been found that each cell being tested has its advantages and drawbacks, owing to unique molecular mechanisms of action. This has led to the concept of combined transplantation of two or more cells.
The transplantation of various types of autologous or allogeneic stem/progenitor cells, including embryonic and induced pluripotent stem cells, has shown promising therapeutic outcomes in animal models of neurological diseases. Such findings are translating into revenue opportunities for companies in the placental stem cell therapy market.
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Analysts’ Viewpoint
Mesenchymal stem cells are emerging as powerful immunomodulators that are playing a key role in advancements made for the treatment of severe COVID-19 patients. MSC-based therapies hold future prospects for companies in the placental stem cell therapy market to create therapeutics for bronchopulmonary dysplasia (BPD) in infants born prematurely. MSCs have proven paracrine activity, which helps migrate toward inflamed sites and improves outcomes in patients suffering from neurological disorders. Ethical issues and immune mediated rejection of transplanted cells are posing as hurdles in the treatment of congenital metabolic diseases. Hence, companies should increase the production of human amniotic epithelial cells (hAECs) that are emerging as an alternative to hepatocyte transplantation (HT) for patients suffering from congenital metabolic diseases.
Placental Stem Cell Therapy Market: Overview
The global placental stem cell therapy market for the historical period 2018–2019 and the forecast period of 2020–2030, prominence in treatment of age-related disorders/diseases and increase in awareness about stem cell therapies are projected to drive the global placental stem cell therapy market in the near future
According to the report, the global placental stem cell therapy market was valued at US$ 0.5 Bn in 2019. It is anticipated to expand at a CAGR of 20% from 2020 to 2030.
Regenerative Ability to Develop into Other Types of Cells to Drive Global Market
Placental therapy is being used to promote recovery from diseases and tissue regeneration since the early 1900s. Since then, placental stem cell therapy has been applied in various clinical applications, as it has exhibited remarkable therapeutic attributes, ranging from anti-oxidant, anti-microbial, anti-inflammatory, pain reduction, hair growth promotion, health improvement, and cellular proliferation to tissue regeneration and wound healing properties in vivo. This review further summarizes historical aspects, cellular mechanism, nutrient content, and therapeutics properties of the placenta.
Placental stem cells offer the potential to treat rare diseases or conditions for which few treatments exist. Sometimes called the body’s “master cells,” these cells can develop into blood, brain, bones, and all of the body’s organs.
These have the potential to repair, restore, replace, and regenerate cells, and could possibly be used to treat several medical conditions and diseases
Placental stem cell therapy is quite useful for the cure of diseases such as Alzheimer’s disease
According to the WHO, worldwide, around 50 million people have dementia and nearly 10 million new cases are recorded every year. Alzheimer’s disease is a highly common form of dementia and contributes to 60% to 70% of cases.
Ease of Procurement
Placenta is a vascular organ with a known duration of life, and is only developed during the occurrence of pregnancy. It attaches to the uterine wall and the umbilical cord, which connects between the mother and the fetus, thereby supporting the growth and development of the fetus.
Placenta plays an important role in transfer of gases, nutrients, and removal of waste products during pregnancy, which is vital for the sustenance of the fetus
Placenta stem cells also provide additional benefit as compared to that offered by other tissues. These cells are easy to procure, with no harm to the mother or the baby. There are also no ethical issues associated with obtaining placenta, as it is considered a biological waste after birth.
Placenta has high cell yield and is less exposed to infection, as it comes from an infection-naïve environment. This makes rendering any disease transmission less likely. This factor is considered a major driver of the placental stem cell therapy market.
Rise in the number of storage banks and the awareness among people are key factors boosting the adoption of placental stem cell therapy
Increase in Awareness about Stem Cell Therapies
Several programs have been conducted to spread awareness about stem cell therapies and educate about the ethical aspects in the field
Every October, the global stem cell community comes together to promote appreciation and understanding of stem cell research on Stem Cell Awareness Day
In emerging countries, such as India, awareness and acceptance for stem cell therapy are increasing rapidly
In 2016, NeuroGen Brain and Spine Institute conducted awareness programs about stem cell therapy in Karnataka (India) and other neighboring states. Thus far, the institute has successfully treated over 800 patients.
Competition Landscape
This report profiles major players operating in the global placental stem cell therapy market based on various attributes such as company overview, financial overview, product portfolio, business strategies, and recent developments
The global placental stem cell therapy market is moderately fragmented, with the presence of a large number of leading players in the global market and several small players in regional markets. Top players hold a major share of the global placental stem cell therapy market.
Prominent players operating in the global placental stem cell therapy market include
- Lifebank Stem Cell Banking
- Celularity, Inc.
- Americord Registry
- ReeLabs Pvt. Ltd.
- Pluristem Therapeutics, Inc.
- Mesoblast Limited
- ReNeuron Group plc
- Athersys, Inc.
The report on the global placental stem cell therapy market discusses individual strategies, followed by company profiles of providers of stem cell therapy. The competition landscape section has been included in the report to provide readers with a dashboard view and a company market share analysis of key players operating in the global placental stem cell therapy market.
Key Questions Answered in Placental Stem Cell Therapy Market Report
- What is the sales/revenue generated by the placental stem cell therapy market across all regions during the forecast period?
- What are the opportunities in the global placental stem cell therapy market?
- What are major drivers, restraints, opportunities, and threats in the market?
- Which regional market is set to expand at the fastest CAGR during the forecast period?
- Which drug class segment is expected to generate the highest revenue globally in 2030? Which segment is projected to expand at the highest CAGR during the forecast period?
- What are the market positions of different companies operating in the global market?
Placental Stem Cell Therapy Market – Segmentation
Application
- Hematologic Malignancies and Disorders
- Congenital Immunodeficiency Disorders
- Metabolic Disorders
- Neurological Disorders
End User
- Hospitals & Specialty Clinics
- Clinical Research Organizations
- Research Institutes & Academies
Region
- North America
- Europe
- Asia Pacific
- Latin America
TABLE OF CONTENT
1. Preface
1.1. Market Definition and Scope
1.2. Market Segmentation
1.3. Key Research Objectives
1.4. Research Highlights
2. Assumptions and Research Methodology
3. Executive Summary: Global Placental Stem Cell Therapy Market
4. Market Overview
4.1. Introduction
4.1.1. Application Definition
4.1.2. Industry Evolution / Developments
4.2. Overview
4.3. Market Dynamics
4.3.1. Drivers
4.3.2. Restraints
4.3.3. Opportunities
4.4. Global Placental Stem Cell Therapy Market Analysis and Forecast, 2018–2030
4.4.1. Market Revenue Projections (US$ Mn)
5. Key Insights
5.1. Supply Chain Analysis
5.1.1. Placental Stem Cells Collection & Isolation
5.1.2. Cell processing & Cryo-preservation
5.1.3. Cell Differentiation
5.1.4. Cell Culture and Expansion
5.2. Pipeline Analysis
5.3. Regulatory Scenario, by Region/globally
5.4. Reimbursement Scenario, by Region/globally
5.5. Pricing Analysis, 2019
5.6. COVID-19 Pandemic Impact on Industry
6. Global Placental Stem Cell Therapy Market Analysis and Forecast, by Application
6.1. Introduction & Definition
6.2. Key Findings / Developments
6.3. Global Placental Stem Cell Therapy Market Value Forecast, by Application, 2018–2030
6.3.1. Hematologic Malignancies and Disorders
6.3.2. Congenital Immunodeficiency Disorders
6.3.3. Metabolic Disorders
6.3.4. Neurological Disorders
6.3.5. Others
6.4. Global Placental Stem Cell Therapy Market Attractiveness Analysis, by Application
7. Global Placental Stem Cell Therapy Market Analysis and Forecast, by End-user
7.1. Introduction & Definition
7.2. Key Findings / Developments
7.3. Global Placental Stem Cell Therapy Market Value Forecast, by End-user, 2018–2030
7.3.1. Hospitals & Specialty Clinics
7.3.2. Clinical Research Organizations
7.3.3. Research Institutes & Academies
7.4. Global Placental Stem Cell Therapy Market Attractiveness Analysis, by End-user
8. Global Placental Stem Cell Therapy Market Analysis and Forecast, by Region
8.1. Key Findings
8.2. Global Placental Stem Cell Therapy Market Value Forecast, by Region
8.2.1. North America
8.2.2. Europe
8.2.3. Asia Pacific
8.2.4. Latin America
8.2.5. Middle East & Africa
8.3. Global Placental Stem Cell Therapy Market Attractiveness Analysis, by Country/Region
9. North America Placental Stem Cell Therapy Market Analysis and Forecast
9.1. Introduction
9.1.1. Key Findings
9.2. North America Placental Stem Cell Therapy Market Value Forecast, by Application, 2018–2030
9.2.1. Hematologic Malignancies and Disorders
9.2.2. Congenital Immunodeficiency Disorders
9.2.3. Metabolic Disorders
9.2.4. Neurological Disorders
9.2.5. Others
9.3. North America Placental Stem Cell Therapy Market Value Forecast, by End-user, 2018–2030
9.3.1. Hospitals & Specialty Clinics
9.3.2. Clinical Research Organizations
9.3.3. Research Institutes & Academies
9.4. North America Placental Stem Cell Therapy Market Value Forecast, by Country, 2018–2030
9.4.1. U.S.
9.4.2. Canada
9.5. North America Placental Stem Cell Therapy Market Attractiveness Analysis
9.5.1. By Application
9.5.2. By End-user
9.5.3. By Country
10. Europe Placental Stem Cell Therapy Market Analysis and Forecast
10.1. Introduction
10.1.1. Key Findings
10.2. Europe Placental Stem Cell Therapy Market Value Forecast, by Application, 2018–2030
10.2.1. Hematologic Malignancies and Disorders
10.2.2. Congenital Immunodeficiency Disorders
10.2.3. Metabolic Disorders
10.2.4. Neurological Disorders
10.2.5. Others
10.3. Europe Placental Stem Cell Therapy Market Value Forecast, by End-user, 2018–2030
10.3.1. Hospitals & Specialty Clinics
10.3.2. Clinical Research Organizations
10.3.3. Research Institutes & Academies
10.4. Europe Placental Stem Cell Therapy Market Value Forecast, by Country/Sub-region, 2018–2030
10.4.1. Germany
10.4.2. U.K.
10.4.3. France
10.4.4. Spain
10.4.5. Italy
10.4.6. Rest of Europe
10.5. Europe Placental Stem Cell Therapy Market Attractiveness Analysis
10.5.1. By Application
10.5.2. By End-user
10.5.3. By Country/Sub-region
11. Asia Pacific Placental Stem Cell Therapy Market Analysis and Forecast
11.1. Introduction
11.1.1. Key Findings
11.2. Asia Pacific Placental Stem Cell Therapy Market Value Forecast, by Application, 2018–2030
11.2.1. Hematologic Malignancies and Disorders
11.2.2. Congenital Immunodeficiency Disorders
11.2.3. Metabolic Disorders
11.2.4. Neurological Disorders
11.2.5. Others
11.3. Asia Pacific Placental Stem Cell Therapy Market Value Forecast, by End-user, 2018–2030
11.3.1. Hospitals & Specialty Clinics
11.3.2. Clinical Research Organizations
11.3.3. Research Institutes & Academies
11.4. Asia Pacific Placental Stem Cell Therapy Market Value Forecast, by Country/Sub-region, 2018–2030
11.4.1. China
11.4.2. Japan
11.4.3. India
11.4.4. Australia & New Zealand
11.4.5. Rest of Asia Pacific
11.5. Asia Pacific Placental Stem Cell Therapy Market Attractiveness Analysis
11.5.1. By Application
11.5.2. By End-user
11.5.3. By Country/Sub-region
12. Latin America Placental Stem Cell Therapy Market Analysis and Forecast
12.1. Introduction
12.1.1. Key Findings
12.2. Latin America Placental Stem Cell Therapy Market Value Forecast, by Application, 2018–2030
12.2.1. Hematologic Malignancies and Disorders
12.2.2. Congenital Immunodeficiency Disorders
12.2.3. Metabolic Disorders
12.2.4. Neurological Disorders
12.2.5. Others
12.3. Latin America Placental Stem Cell Therapy Market Value Forecast, by End-user, 2018–2030
12.3.1. Hospitals & Specialty Clinics
12.3.2. Clinical Research Organizations
12.3.3. Research Institutes & Academies
12.4. Latin America Placental Stem Cell Therapy Market Value Forecast, by Country/Sub-region, 2018–2030
12.4.1. Brazil
12.4.2. Mexico
12.4.3. Rest of Latin America
12.5. Latin America Placental Stem Cell Therapy Market Attractiveness Analysis
12.5.1. By Application
12.5.2. By End-user
12.5.3. By Country//Sub-region
13. Middle East & Africa Placental Stem Cell Therapy Market Analysis and Forecast
13.1. Introduction
13.1.1. Key Findings
13.2. Middle East & Africa Placental Stem Cell Therapy Market Value Forecast, by Application, 2018–2030
13.2.1. Hematologic Malignancies and Disorders
13.2.2. Congenital Immunodeficiency Disorders
13.2.3. Metabolic Disorders
13.2.4. Neurological Disorders
13.2.5. Others
13.3. Middle East & Africa Placental Stem Cell Therapy Market Value Forecast, by End-user, 2018–2030
13.3.1. Hospitals & Specialty Clinics
13.3.2. Clinical Research Organizations
13.3.3. Research Institutes & Academies
13.4. Middle East & Africa Placental Stem Cell Therapy Market Value Forecast, by Country/Sub-region, 2018–2030
13.4.1. GCC Countries
13.4.2. South Africa
13.4.3. Rest of Middle East & Africa
13.5. Middle East & Africa Placental Stem Cell Therapy Market Attractiveness Analysis
13.5.1. By Application
13.5.2. By End-user
13.5.3. By Country/Sub-region
14. Competition Landscape
14.1. Market Player – Competition Matrix (by tier and size of companies)
14.2. Market Share Analysis, by Company, 2019
14.3. Company Profiles
14.3.1. Lifebank Stem Cell Banking
14.3.1.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.1.2. Product Portfolio
14.3.1.3. SWOT Analysis
14.3.1.4. Strategic Overview
14.3.2. Celularity, Inc.
14.3.2.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.2.2. Product Portfolio
14.3.2.3. SWOT Analysis
14.3.2.4. Strategic Overview
14.3.3. Americord Registry
14.3.3.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.3.2. Product Portfolio
14.3.3.3. SWOT Analysis
14.3.3.4. Strategic Overview
14.3.4. ReeLabs Pvt. Ltd.
14.3.4.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.4.2. Product Portfolio
14.3.4.3. SWOT Analysis
14.3.4.4. Strategic Overview
14.3.5. Pluristem Therapeutics, Inc.
14.3.5.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.5.2. Product Portfolio
14.3.5.3. SWOT Analysis
14.3.5.4. Strategic Overview
14.3.6. Mesoblast Limited
14.3.6.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.6.2. Product Portfolio
14.3.6.3. SWOT Analysis
14.3.6.4. Strategic Overview
14.3.7. ReNeuron Group plc
14.3.7.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.7.2. Product Portfolio
14.3.7.3. SWOT Analysis
14.3.7.4. Strategic Overview
14.3.8. Athersys, Inc.
14.3.8.1 Company Overview (HQ, Business Segments, Employee Strength)
14.3.8.2. Product Portfolio
14.3.8.3. SWOT Analysis
14.3.8.4. Strategic Overview
14.3.9. Other Prominent Key Players
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